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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2001-2-23
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pubmed:abstractText |
We investigated the mRNA expression of the human endogenous retrovirus ERV3 (HERV-R) in several normal and corresponding tumor tissues. The env gene of ERV3 is expressed as mRNA in several tissues. Comparison of ERV3 mRNA expression by Northern analyses, revealed a non-systematic variation. Expression was shown to be particularly high in the adrenal gland and some cases of lung cancer. This tissue-tropism should be seen in relation to the high expression previously found in syncytiotrophoblasts in placenta and sebaceous glands of the skin, suggesting profound influences by steroid hormonal regulation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1019-6439
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
309-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9458354-Blotting, Northern,
pubmed-meshheading:9458354-Endogenous Retroviruses,
pubmed-meshheading:9458354-Gene Expression,
pubmed-meshheading:9458354-Genes, Viral,
pubmed-meshheading:9458354-Humans,
pubmed-meshheading:9458354-In Situ Hybridization,
pubmed-meshheading:9458354-Neoplasms,
pubmed-meshheading:9458354-Nucleic Acid Hybridization,
pubmed-meshheading:9458354-Polymorphism, Genetic,
pubmed-meshheading:9458354-RNA, Messenger,
pubmed-meshheading:9458354-RNA, Viral,
pubmed-meshheading:9458354-Tissue Distribution,
pubmed-meshheading:9458354-Trophoblasts
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pubmed:year |
1998
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pubmed:articleTitle |
Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues.
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pubmed:affiliation |
Department of Pathology, Uppsala University Hospital, S-751 85 Uppsala, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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