Linked Life Data

9442362

Source:http://linkedlifedata.com/resource/pubmed/id/9442362

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-3-11
pubmed:abstractText
The application of modern techniques in molecular genetics to classic diseases in clinical nephrology is highlighted by the recent description of the molecular basis of Bartter's and Gitelman's syndromes. A series of detailed studies are described that have resulted in the identification of specific mutations in four different genes, each of which causes hypokalemic alkalosis, salt wasting and hypotension. The importance of these genetic studies in understanding renal physiology and the regulation of blood pressure, and in developing new therapeutic strategies is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1062-4821
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-7
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Ion transporter mutations in Gitelman's and Bartter's syndromes.
pubmed:affiliation
Howard Hughes Medical Institute, Department of Medicine (Nephrology), Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA. david.simon@yale.edu
pubmed:publicationType
Journal Article, Review