rdf:type |
|
lifeskim:mentions |
umls-concept:C0001511,
umls-concept:C0011945,
umls-concept:C0015350,
umls-concept:C0016055,
umls-concept:C0022984,
umls-concept:C0030705,
umls-concept:C0039194,
umls-concept:C0205216,
umls-concept:C0449432,
umls-concept:C1179435,
umls-concept:C1332714,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248
|
pubmed:issue |
12
|
pubmed:dateCreated |
1998-2-19
|
pubmed:abstractText |
Cell-mediated immunity is impaired in uraemia. The recognition and ensuing interactions of immune cells, such as CD4+ T lymphocytes, with adhesive glycoproteins of the extra-cellular matrix (ECM) are mediated by integrins of the beta 1 subfamily. We have previously demonstrated that uraemic sera inhibit the proliferation and adhesion of normal CD4+ T cells to ECM components. In the present study, the adhesive capacity of CD4+ T lymphocytes of dialyzed patients (both haemodialysis [HD] and continuous ambulatory peritoneal dialysis [CAPD] was evaluated.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0931-0509
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2618-22
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9430861-Adult,
pubmed-meshheading:9430861-Aged,
pubmed-meshheading:9430861-Antigens, CD29,
pubmed-meshheading:9430861-CD4-Positive T-Lymphocytes,
pubmed-meshheading:9430861-Cell Adhesion,
pubmed-meshheading:9430861-Cell Membrane,
pubmed-meshheading:9430861-Extracellular Matrix,
pubmed-meshheading:9430861-Female,
pubmed-meshheading:9430861-Fibronectins,
pubmed-meshheading:9430861-Humans,
pubmed-meshheading:9430861-Laminin,
pubmed-meshheading:9430861-Male,
pubmed-meshheading:9430861-Middle Aged,
pubmed-meshheading:9430861-Renal Replacement Therapy
|
pubmed:year |
1997
|
pubmed:articleTitle |
Diminished adhesion of CD4+ T cells from dialysis patients to extracellular matrix and its components fibronectin and laminin.
|
pubmed:affiliation |
Department of Nephrology, Meir Hospital, Kfar Saba, Israel.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|