rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1998-2-5
|
pubmed:abstractText |
Withdrawal from the cell cycle as cells begin to differentiate is accomplished by the downregulation of cyclin-dependent kinase activities in G1 phase. Recent analysis of loss-of-function mutations in flies, worms, and mice has provided insight into the roles of various negative regulators of G1 phase in developing organisms.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0955-0674
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
773-81
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:9425341-Animals,
pubmed-meshheading:9425341-Caenorhabditis elegans,
pubmed-meshheading:9425341-Cell Cycle Proteins,
pubmed-meshheading:9425341-Cell Differentiation,
pubmed-meshheading:9425341-Cell Division,
pubmed-meshheading:9425341-Cyclin-Dependent Kinase Inhibitor p27,
pubmed-meshheading:9425341-Cyclin-Dependent Kinases,
pubmed-meshheading:9425341-Drosophila,
pubmed-meshheading:9425341-G1 Phase,
pubmed-meshheading:9425341-Mice,
pubmed-meshheading:9425341-Microtubule-Associated Proteins,
pubmed-meshheading:9425341-S Phase,
pubmed-meshheading:9425341-Tumor Suppressor Proteins
|
pubmed:year |
1997
|
pubmed:articleTitle |
Controlling cell proliferation in differentiating tissues: genetic analysis of negative regulators of G1-->S-phase progression.
|
pubmed:affiliation |
Department of Biological Chemistry, School of Medicine, University of California at Los Angeles 90095, USA. zavitz@hhmi.ucla.edu
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|