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pubmed:abstractText |
The cause of growth retardation in trisomy 21 and other autosomal trisomies is not known, but may be the result of defective cell proliferation, slowing of the cell cycle, or placental structural abnormalities. Abnormalities of the fetal cell cycle may be reflected in placental growth and can be detected using proliferating cell nuclear antigen (PCNA).
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pubmed:affiliation |
Department of Pathology, Hutzel Hospital, Wayne State University School of Medicine, Detroit, Mich., USA.
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