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pubmed:abstractText |
Extralysosomal degradation of proteins is carried out by proteases complex (proteasomes), calcium dependent calpains, proteases of the rough endoplasmatic reticulum and proteases of the cellular membrane. It depends on a limited proteolysis and includes the main enzymatic proteins, hormones, growth factors and cytoskeletal proteins. Thus it plays an important regulatory role in the metabolism and formation of cellular structures.
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