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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1997-12-4
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pubmed:abstractText |
To investigate the presence, number, and level of expression of tumor necrosis factor receptors (TNF-R) in normal and osteoarthritic (OA) human synovial fibroblasts; to examine which receptor isotype mediates the biological response of these cells to TNF-alpha; and to study homologous regulatory mechanisms of TNF-R by TNF-alpha.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Blocking,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0315-162X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1985-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9330943-Aged,
pubmed-meshheading:9330943-Antibodies, Blocking,
pubmed-meshheading:9330943-Antigens, CD,
pubmed-meshheading:9330943-Cyclooxygenase 2,
pubmed-meshheading:9330943-Dinoprostone,
pubmed-meshheading:9330943-Fibroblasts,
pubmed-meshheading:9330943-Flow Cytometry,
pubmed-meshheading:9330943-Humans,
pubmed-meshheading:9330943-Isoenzymes,
pubmed-meshheading:9330943-Membrane Proteins,
pubmed-meshheading:9330943-Middle Aged,
pubmed-meshheading:9330943-Osteoarthritis,
pubmed-meshheading:9330943-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:9330943-Radioligand Assay,
pubmed-meshheading:9330943-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:9330943-Receptors, Tumor Necrosis Factor, Type I,
pubmed-meshheading:9330943-Synovial Membrane,
pubmed-meshheading:9330943-Tumor Necrosis Factor-alpha
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pubmed:year |
1997
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pubmed:articleTitle |
Osteoarthritic synovial fibroblasts possess an increased level of tumor necrosis factor-receptor 55 (TNF-R55) that mediates biological activation by TNF-alpha.
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pubmed:affiliation |
Osteoarthritis Research Unit, Louis-Charles Simard Research Centre, Notre-Dame Hospital, University of Montreal, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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