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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
1997-11-18
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pubmed:abstractText |
Plasma interleukin-8 (IL-8) interleukin-10 (IL-10), and E-selectin concentrations were studied in 39 neutropenic and 30 non-neutropenic bacteremic patients; 54 nonbacteremic patients were analyzed as controls. Interleukin-8 concentrations were significantly higher in neutropenic than in non-neutropenic bacteremic patients (median 475 vs. 0 pg/ml, p < 0.0001). Median IL-8 and IL-10 levels were higher in bacteremic than in non-bacteremic patients (330 vs. 0 pg/ml, p < 0.0001 and 20 vs. 0 pg/ml, p = 0.04, respectively). In contrast, concentrations of IL-10 were similar in neutropenic and non-neutropenic patients. Median levels of E-selectin were not increased in any of the patient groups. Neutropenic bacteremic patients showed significantly lower concentrations of E-selectin than did non-neutropenic bacteremic patients (p < 0.0001). In conclusion, neutropenic bacteremic patients had significantly higher concentrations of IL-8 than non-neutropenic bacteremic patients. Levels of IL-10 were higher in bacteremic than in nonbacteremic patients, but neutropenic and non-neutropenic patients had similar levels of IL-10. Increased levels of E-selectin were not found in any of the patient groups, although neutropenic patients with bacteremia had lower concentrations than did non-neutropenic patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
587-91
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9323470-Adult,
pubmed-meshheading:9323470-Aged,
pubmed-meshheading:9323470-Bacteremia,
pubmed-meshheading:9323470-Biological Markers,
pubmed-meshheading:9323470-Chi-Square Distribution,
pubmed-meshheading:9323470-E-Selectin,
pubmed-meshheading:9323470-Female,
pubmed-meshheading:9323470-Gram-Negative Bacteria,
pubmed-meshheading:9323470-Gram-Positive Bacteria,
pubmed-meshheading:9323470-Humans,
pubmed-meshheading:9323470-Immunoenzyme Techniques,
pubmed-meshheading:9323470-Interleukin-10,
pubmed-meshheading:9323470-Interleukin-8,
pubmed-meshheading:9323470-Male,
pubmed-meshheading:9323470-Middle Aged,
pubmed-meshheading:9323470-Neutropenia,
pubmed-meshheading:9323470-Sensitivity and Specificity
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pubmed:year |
1997
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pubmed:articleTitle |
Plasma interleukin-8, interleukin-10, and E-selectin levels in neutropenic and non-neutropenic bacteremic patients.
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pubmed:affiliation |
Department of Surgery/Intensive Care Unit, Helsinki University Central Hospital, Finland.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|