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pubmed-article:9323080pubmed:abstractTextGrowth factors such as platelet-derived growth factor (PDGF) have been postulated to be important mediators of neointimal formation in balloon-injured artery. Binding of growth factors to their receptors activates intrinsic receptor tyrosine kinase, resulting in tyrosine phosphorylation of receptors themselves and cellular substrate proteins. We investigated in vivo activities of growth factors by determining the extent of tyrosine phosphorylation of growth factor receptors and substrate proteins in injured artery.lld:pubmed
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pubmed-article:9323080pubmed:articleTitleStimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening.lld:pubmed
pubmed-article:9323080pubmed:affiliationDepartment of Cardiovascular Biology, Faculty of Medicine, University of Tokyo, Japan.lld:pubmed
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