Source:http://linkedlifedata.com/resource/umls/id/C0071253
MSH: Specific receptors on cell membranes that react with PLATELET-DERIVED GROWTH FACTOR, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA) and the beta PDGF receptor (RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced dimerization or heterodimerization of PDGF receptor types.,NCI: A cell surface protein that has tyrosine-kinase activity. This receptor specifically binds to platelet derived growth factor, and its analogs and antagonists. Ligand binding causes homodimerization or heterodimerization, resulting in receptor activation.