Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1997-9-26
|
| pubmed:abstractText |
The interaction of 13 antibiotics with human serum albumin was studied by charge-transfer reversed-phase thin-layer chromatography in neutral, acidic, basic and ionic environments (NaCl and MgCl2) and the relative strength of interaction was calculated. The pH and the presence of mono- and divalent cations markedly influenced the strength of interaction. The capacity of antibiotics to interact with HSA also considerably depended on their chemical structure.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0021-9673
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
|
| pubmed:volume |
776
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
31-6
|
| pubmed:dateRevised |
2009-1-15
|
| pubmed:meshHeading |
pubmed-meshheading:9286075-Anti-Bacterial Agents,
pubmed-meshheading:9286075-Chemistry, Physical,
pubmed-meshheading:9286075-Chromatography, Thin Layer,
pubmed-meshheading:9286075-Humans,
pubmed-meshheading:9286075-Hydrogen-Ion Concentration,
pubmed-meshheading:9286075-Physicochemical Phenomena,
pubmed-meshheading:9286075-Protein Binding,
pubmed-meshheading:9286075-Serum Albumin,
pubmed-meshheading:9286075-Spectrophotometry, Ultraviolet
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Study of the binding of antibiotics to human serum albumin by charge-transfer chromatography.
|
| pubmed:affiliation |
Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest, Hungary.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|