Linked Life Data

9278912

Source:http://linkedlifedata.com/resource/pubmed/id/9278912

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-10-9
pubmed:abstractText
A broad range of residual lumbar spinal cord blood flows assessed by laser-Doppler flowmetry (rSCBF, 0-78%) was achieved by snare occlusion of the descending aorta and additional blood-volume reduction for 1-10 min in spinal cats (n = 30; 238 trials). The period of complete reflex suppression (delay until recovery) that revealed some correlation to duration (r = 0.72) and depth (r = -0.36) of ischemia showed comparable durations in mono- and polysynaptic reflexes, whereas it was significantly less for the cord dorsum potential (CDP). With rSCBF values > 50-60% reflexes and > 45%, the CDP was rarely abolished, irrespective of the duration of ischemia. The threshold of duration for a complete loss of reflex responses was found to be approximately 1 min of ischemia. The influence of rSCBF and duration of ischemia on the occurrence of incomplete recoveries of reflexes was assessed simultaneously in a logistic regression model. Compared with periods of ischemia of 3 min, all longer durations showed a steep risk gradient for incomplete recoveries; an increment of 10% in rSCBF led to a risk reduction for incomplete recoveries of nearly 25%. These findings were significant (p < 0.001) and indicated that blood-flow thresholds and limits for the development of neurologic deficits of the spinal cord are comparable to those of the brain, with the important difference that the blood-flow reserve of the spinal cord is smaller.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0895-0385
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
288-95
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Critical levels of spinal cord blood flow and duration of ischemia for the acute recovery of segmental spinal cord responses in cats.
pubmed:affiliation
Institute of Physiology, University of Göttingen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't