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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-9-30
|
| pubmed:abstractText |
There is wide variation in reported risk factors for HIV incidence among injecting drug users by community. Available HIV seroprevalence and incidence data indicate that nearly 60% of HIV infection is associated with injecting drug use in Connecticut and 48% in Massachusetts. Using 12-month follow-up data on 354 initially HIV-negative New England (Massachusetts and Connecticut) methadone treatment clients, we assessed the association between baseline drug use practices, sexual behavior, partner behaviors, and client-reported HIV infection during follow-up. Variables that predicted client-reported positive HIV antibody test results were modeled by Cox proportional hazards regression. HIV infection among those tested was 14.2 per 100 person years (PY) [95% Confidence interval (CI) = 9.5 to 21.3]. For each injection the relative risk (RR) was 1.1 (95% CI = 1.1 to 1.2), for males 3.0 (95% CI = 1.2 to 7.3), for blacks 5.0 (95% CI = 1.6 to 15.5), for Hispanics 3.6 (95% CI = 1.2 to 10.5). Men who used more than one unclean needle per day and had an HIV-infected steady partner had an RR of 28.4 (95% CI = 4.4 to 176.4). For women, using speedball (RR = 6.1, 95% CI = 1.2 to 38.8) and being black (RR = 4.4, 95% CI = 1.0 to 19.8) predicted self-reported HIV infection; having a steady partner who ever injected increased this risk substantially (RR = 65.3, 95% CI = 4.0 to 1046.5). These findings for IDUs in Massachusetts and Connecticut indicate that risk factors for HIV infection for men are consistent with expected transmission by unclean needles with an HIV-infected partner, but a preference for using speedball predicted HIV infection among women IDUs.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0095-2990
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
397-411
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9261488-Adult,
pubmed-meshheading:9261488-Cocaine,
pubmed-meshheading:9261488-Confidence Intervals,
pubmed-meshheading:9261488-Connecticut,
pubmed-meshheading:9261488-Cross-Sectional Studies,
pubmed-meshheading:9261488-Female,
pubmed-meshheading:9261488-Follow-Up Studies,
pubmed-meshheading:9261488-HIV Infections,
pubmed-meshheading:9261488-Heroin Dependence,
pubmed-meshheading:9261488-Humans,
pubmed-meshheading:9261488-Incidence,
pubmed-meshheading:9261488-Male,
pubmed-meshheading:9261488-Massachusetts,
pubmed-meshheading:9261488-Methadone,
pubmed-meshheading:9261488-Needle Sharing,
pubmed-meshheading:9261488-Prospective Studies,
pubmed-meshheading:9261488-Risk,
pubmed-meshheading:9261488-Sexual Behavior,
pubmed-meshheading:9261488-Sexual Partners,
pubmed-meshheading:9261488-Substance Abuse, Intravenous,
pubmed-meshheading:9261488-Substance-Related Disorders
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
HIV infection risks, behaviors and methadone treatment: client-reported HIV infection in a follow-up study of injecting drug users in New England.
|
| pubmed:affiliation |
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
|
| pubmed:publicationType |
Journal Article
|