Methadone

Source:http://linkedlifedata.com/resource/umls/id/C0025605

MSH: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3),CSP: synthetic narcotic possessing pharmacologic actions similar to those of morphine and heroin and almost equal addiction liability; used as an analgesic and as a narcotic abstinence syndrome suppressant in the treatment of heroin addition.,NCI: A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine and morphine-like agents. The characteristic morphine-like effects include analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia and physical dependence. However, the detoxification symptoms between morphine-like agents and methadone differ in that the onset of methadone's withdrawal symptoms is slower, the course is mo

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