Linked Life Data

9156645

Source:http://linkedlifedata.com/resource/pubmed/id/9156645

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-5-21
pubmed:abstractText
Many clinical studies have been performed investigating corneal endothelial cell loss after penetrating keratoplasty using different preservation methods. Most studies, however, included variable follow-up intervals, neglecting the dynamic cell loss over the course of time. The aim of this study was to perform endothelial cell evaluation 5 years after penetrating keratoplasty using two different storage methods. Fifty-four patients were examined 5.2 (+/-0.5) or 4.9 (+/-0.6) years after surgery. Twenty-four patients had received a cornea stored in a moist chamber, 30 patients a cornea preserved by organ culture. All corneas had remained clear in the follow-up period. The follow-up periods did not differ significantly (P = 0.26). The post-mortem time of moist-chamber-stored tissue was significantly lower (P < 0.001), endothelial cell density significantly higher (P < 0.001) in organ-culture-preserved corneas. Donor age (P = 0.64) and patient age (P = 0.046) did not differ significantly. Average corneal endothelial cell density was 1070 (+/-499) cells/mm2 using moist chamber stored and 1095 (+/-497) cells/mm2 using organ-culture-preserved tissue (P = 0.82). Five years after penetrating keratoplasty, we were not able to find significant differences in corneal endothelial cell density using either moist chamber or organ-culture-preserved corneas. We prefer to use organ culture since there is a lower incidence of primary graft failure, tissue with longer postmortem times can be used, and surgery can be scheduled.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0941-293X
pubmed:author
pubmed:issnType
Print
pubmed:volume
94
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
90-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Development of endothelium cell density using fresh and organ cultured tissue. 5 years after penetrating keratoplasty].
pubmed:affiliation
Augenklinik, Medizinische Hochschule Hannover.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract