Linked Life Data

9135267

Source:http://linkedlifedata.com/resource/pubmed/id/9135267

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-5-15
pubmed:abstractText
Unabsorbed carbohydrates are fermented by colonic bacteria to short chain fatty acids (SCFA) which are rapidly absorbed, salvaging energy and reducing stool output. There are marked differences between the faecal flora and SCFA of breast fed (BF) and formula fed (FF) infants which may be related to the higher incidence of diarrhoea in FF infants. Part of this effect may be caused by a difference in the ability of the microflora to ferment carbohydrate. To test the hypothesis that BF and FF have different fermentation capacities for simple and complex carbohydrates, in vitro cultures of faeces from healthy infants (2-10 weeks; 11 BF, 11 FF) containing glucose, lactose, raftilose (a fructo-oligosaccharide), or soybean polysaccharide were incubated anaerobically. Results were compared with those of adult faecal cultures using the same carbohydrates. Cultures of faeces from BF and FF infants produced comparable amounts of total SCFA in all cultures. These cultures produced less SCFA than those from adult faeces and produced very little SCFA from complex carbohydrate. BF cultures produced more acetic acid than FF in all cultures, whereas FF cultures produced more propionate with sugars and more butyrate with raftilose. Both groups of infants produced less butyrate than adults in all cultures. Thus it is unlikely that a lower ability to ferment carbohydrate is a major cause of increased risk of diarrhoea in FF fed infants but individual SCFA production may be important.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-2105113, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-2163190, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-2314945, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-2344923, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-2696432, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-3345894, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-3389128, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-3397847, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-6408235, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-7084619, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-7351283, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-7361693, http://linkedlifedata.com/resource/pubmed/commentcorrection/9135267-8086719
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1468-2044
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
249-53
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
In vitro fermentation of carbohydrate by breast fed and formula fed infants.
pubmed:affiliation
Department of Human Nutrition, Glasgow University.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro