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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1997-3-27
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pubmed:databankReference |
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pubmed:abstractText |
Kinesin-73 cDNA was shown to encode a kinesin heavy chain protein that contains an N-terminal motor domain and a long central region that lacks extensive coiled-coils. The amino acid sequence of the motor domain of kinesin-73 protein is most closely related to the motor domains of Caenorhabditis elegans unc-104 and mouse KIF1A. The central region of kinesin-73 protein also is related to unc-104 and KIF1A, but the homology is lower than that of the motor domain. The C-terminal region of kinesin-73 protein contains a cytoskeleton associated protein Gly-rich domain, which is a putative microtubule binding site that is present in some cytoskeleton or dynein-associated proteins. Kinesin-73 mRNA was shown by in situ hybridization to be maternally expressed and widely distributed in the syncytial blastoderm embryo. However, later in Drosophila embryo development, expression of the kinesin-73 gene becomes restricted mostly to the central and peripheral nervous systems.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1356075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1600942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1710172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1827919,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1836789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1846075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1905801,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-1924306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2031185,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2126155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2144792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2476281,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2522352,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2558049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2819881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-2827169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-3302672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-6325925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7525600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7528108,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7539720,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7556915,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7730406,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7800833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-7906398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8227131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8352594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8480366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8528901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8580705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8601599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8661001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9037010-8700828
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1086-91
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9037010-Amino Acid Sequence,
pubmed-meshheading:9037010-Animals,
pubmed-meshheading:9037010-Animals, Genetically Modified,
pubmed-meshheading:9037010-Base Sequence,
pubmed-meshheading:9037010-Cloning, Molecular,
pubmed-meshheading:9037010-Drosophila,
pubmed-meshheading:9037010-Drosophila Proteins,
pubmed-meshheading:9037010-Genomic Library,
pubmed-meshheading:9037010-In Situ Hybridization,
pubmed-meshheading:9037010-Insect Proteins,
pubmed-meshheading:9037010-Kinesin,
pubmed-meshheading:9037010-Mice,
pubmed-meshheading:9037010-Molecular Sequence Data,
pubmed-meshheading:9037010-Nerve Tissue Proteins,
pubmed-meshheading:9037010-Nervous System,
pubmed-meshheading:9037010-Protein Conformation,
pubmed-meshheading:9037010-Sequence Analysis, DNA,
pubmed-meshheading:9037010-Sequence Homology, Amino Acid,
pubmed-meshheading:9037010-Tissue Distribution
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pubmed:year |
1997
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pubmed:articleTitle |
Kinesin-73 in the nervous system of Drosophila embryos.
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pubmed:affiliation |
Laboratory of Biochemical Genetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892-4036, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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