Linked Life Data

9026524

Source:http://linkedlifedata.com/resource/pubmed/id/9026524

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-2-20
pubmed:abstractText
Data on the physico-chemical properties of carotenoids in biological emulsions are essential to our knowledge of carotenoid metabolism. Therefore, we determined the behavior of carotenoids in phospholipid-stabilized triglyceride emulsions, a model for biological emulsions such as dietary emulsions, triglyceride-rich lipoproteins, and intracellular storage droplets. The solubility of beta-carotene (a model for apolar carotenoids, carotenes) in pure bulk triglycerides (0.112 to 0.141 wt % according to triglycerides) was significantly higher than zeaxanthin (a model for polar carotenoids, xanthophylls) (0.022 to 0.088 wt %). The solubility of both carotenoids increased when the chain-length of the triglycerides' fatty acids decreased. The amount of zeaxanthin associated with lipid droplet dramatically increased in phospholipid-triglyceride droplets as compared to the pure corresponding triglyceride droplets, whereas the amount of beta-carotene associated with lipid droplets increased only slightly beta-Carotene distributed almost exclusively in the core of triolein-lecithin-carotenoid droplets, while zeaxanthin distributed preferentially at the droplet's surface. A significant percentage (8.3%) of zeaxanthin was spontaneously transferred from lipid droplets to aqueous phase and the remaining part was transferred during triglyceride hydrolysis catalysed by pancreatic lipase, while beta-carotene absolutely required triglyceride lipolysis to be transferred to the aqueous phase. Our results show that polar and apolar carotenoids behave differently in biological emulsions. They further our understanding of the bioavailability of polar and apolar carotenoids and of their distribution between lipoprotein particles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-2275
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
250-61
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Carotenoids in biological emulsions: solubility, surface-to-core distribution, and release from lipid droplets.
pubmed:affiliation
INRA, Unité Maladies Métaboliques, Centre de Recherche en Nutrition Humaine, Clermont-Ferrand, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't