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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1997-2-27
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pubmed:abstractText |
The fly visual system has served for decades as a model for receptor spectral multiplicity and vitamin A utilization. A diverse armamentarium of structural techniques has dovetailed with convenient electrophysiology, photochemistry, genetics, and molecular biology in Drosophila to facilitate recent progress, which is reviewed here. New data are also presented. Ultrastructure of retinula cells of carotenoid-deprived flies shows that organelles associated with protein biosynthesis, i.e., rough endoplasmic reticulum and Golgi apparatus, are present, while organelles associated with rhabdomere turnover, i.e., multivesicular bodies (MVBs), are rare. Ultrastructure and morphometry suggest that retinoic acid-rearing stimulates membrane export and rhabdomere buildup, even though functional rhodopsin is missing. Confocal microscopy suggests that RH4, one of the ultraviolet rhodopsins, may reside in the previously-described pale fluorescent R7 cells with RH3 in the yellow fluorescent R7 cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1059-910X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
418-30
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9016446-Animals,
pubmed-meshheading:9016446-Drosophila melanogaster,
pubmed-meshheading:9016446-Microscopy, Confocal,
pubmed-meshheading:9016446-Microscopy, Electron,
pubmed-meshheading:9016446-Photoreceptor Cells,
pubmed-meshheading:9016446-Retina,
pubmed-meshheading:9016446-Rhodopsin,
pubmed-meshheading:9016446-Transcription, Genetic,
pubmed-meshheading:9016446-Tretinoin,
pubmed-meshheading:9016446-Vitamin A
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pubmed:year |
1996
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pubmed:articleTitle |
Vitamin A, visual pigments, and visual receptors in Drosophila.
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pubmed:affiliation |
Department of Biology, Saint Louis University, Missouri 63103-2010, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Review
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