Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-12-19
pubmed:abstractText
An overview is given of the phenotype of mice with distinct deletions of genes for cytokines and some related proteins, which occur either naturally or as a result of homologous recombination. The use of such knockout mice for investigation of the pathophysiology of experimental disease is summarized. Understanding of the role of a given cytokine in pathogenesis has therapeutic implications, as the pathology may be prevented or attenuated by inhibition of the synthesis, release or activity of that cytokine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0959-9673
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
125-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Gene knockout mice as investigative tools in pathophysiology.
pubmed:affiliation
Institute of Pathology, University of Basel, Switzerland.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't