Source:http://linkedlifedata.com/resource/umls/id/C0599772
MSH: Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.,NCI: Refers to the targeted disruption of a gene within its normal biological context. Utilized to examine the involvement of a gene in a complex biological process.