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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-3-11
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pubmed:abstractText |
We have examined the postnatal development of satellite cells associated with parasympathetic neurons of mouse salivary duct ganglia. The number of satellite cells associated with each neuron was found to increase during the first 8 weeks after birth but remained constant thereafter. This corresponds to the period of maximal growth of the salivary gland that serves as the target organ innervated by these neurons. At all ages examined, the number of satellite cells associated with each neuron was found to be highly correlated with neuronal volume. The development of satellite cells associated with individual identified neurons was followed directly by in vivo video microscopy over several months, and the number of satellite cell nuclei was found to increase in regions of the neuronal surface with increasing numbers of synaptic boutons. These results indicate that the postnatal addition of satellite cells to parasympathetic neurons is linked to neuronal enlargement and that synaptic remodeling occurs in concert with satellite cell development.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0021-9967
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
375
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518-25
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8915846-Animals,
pubmed-meshheading:8915846-Cell Count,
pubmed-meshheading:8915846-Cell Nucleus,
pubmed-meshheading:8915846-Cell Size,
pubmed-meshheading:8915846-Male,
pubmed-meshheading:8915846-Mice,
pubmed-meshheading:8915846-Mice, Inbred Strains,
pubmed-meshheading:8915846-Neuroglia,
pubmed-meshheading:8915846-Neurons,
pubmed-meshheading:8915846-Parasympathetic Nervous System,
pubmed-meshheading:8915846-Poisson Distribution
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pubmed:year |
1996
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pubmed:articleTitle |
Postnatal addition of satellite cells to parasympathetic neurons.
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pubmed:affiliation |
Department of Neurology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. Pomeroy@A1.TCH.Harvard.Edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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