Linked Life Data

8908852

Source:http://linkedlifedata.com/resource/pubmed/id/8908852

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-3-5
pubmed:abstractText
Chlorinated phenols are widely used in the manufacture of biocides and wood preservatives. 2,4-dichlorophenol administered perorally 3 times a week at a dose of 40 mg in 0.2 ml of olive oil per kg of body weight to guinea pigs increased lipid peroxidation in liver and adrenals after 2 weeks of treatment. A high intake of ascorbic acid (50 mg/animal/day) significantly decreased lipid peroxidation in the liver of 2, 4-dichlorophenol treated guinea pigs in comparison to guinea pigs with low ascorbic acid intake (2 mg/animal/day). 2,4-dichlorophenol accumulation was also decreased in the liver of animals with high ascorbic acid intake. Increased daily intake of vitamin C to persons involved in production and use of chlorophenoxy herbicides is recommended.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0019-8366
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
415-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
The effect of 2,4-dichlorophenol on lipid peroxidation in tissues of guinea pigs with different ascorbic acid intake.
pubmed:affiliation
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic. kovacik@enigma.upkm.sanet.sk
pubmed:publicationType
Journal Article