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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-12-12
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pubmed:abstractText |
The effects of infection with respiratory syncytial virus (RSV) on expression of intercellular adhesion molecule (ICAM)-1 was determined in vitro in nasal epithelial cell cultures. Functional consequences of changes in ICAM-1 expression were assessed by measuring adhesion of a human leukaemic T-cell line to RSV-infected epithelial cells. Also, adhesion of phytohaemagglutinin-activated tonsillar lymphocytes (TL) to RSV-infected epithelial cells caused a significant increase in interleukin (IL)-4 or IL-5 production. Release of these cytokines was adhesion dependent as non-adherent TL produced significantly less IL-4 or IL-5. However, no significant difference was observed for IL-2 or interferon-gamma (IFN-gamma) production. These observations suggest that RSV-infected epithelial cells may induce T-helper type-2 (Th2)-like cytokines by mucosal lymphocytes during mucosal infection in vivo.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1352970,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1353976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1370514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1530827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-153087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1672652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1677945,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1753101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-1974032,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-2005091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-2155971,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-2440339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-2538243,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-2538244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-4073668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-6312838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-7525481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-7542091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-7691947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-8228363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-8238534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-8345194,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8881758-8515055
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0019-2805
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
565-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8881758-Adult,
pubmed-meshheading:8881758-Base Sequence,
pubmed-meshheading:8881758-Cell Culture Techniques,
pubmed-meshheading:8881758-Child,
pubmed-meshheading:8881758-Child, Preschool,
pubmed-meshheading:8881758-Cytokines,
pubmed-meshheading:8881758-Humans,
pubmed-meshheading:8881758-Immunity, Mucosal,
pubmed-meshheading:8881758-Intercellular Adhesion Molecule-1,
pubmed-meshheading:8881758-Lymphocytes,
pubmed-meshheading:8881758-Molecular Sequence Data,
pubmed-meshheading:8881758-Nasal Mucosa,
pubmed-meshheading:8881758-Palatine Tonsil,
pubmed-meshheading:8881758-Phytohemagglutinins,
pubmed-meshheading:8881758-Polymerase Chain Reaction,
pubmed-meshheading:8881758-RNA, Messenger,
pubmed-meshheading:8881758-Respiratory Syncytial Virus Infections
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pubmed:year |
1996
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pubmed:articleTitle |
Induction of intercellular adhesion molecule-1 in human nasal epithelial cells during respiratory syncytial virus infection.
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pubmed:affiliation |
Department of Otolaryngology, Akita University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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