Intercellular adhesion molecule 1

Source:http://linkedlifedata.com/resource/umls/id/C0063695

MSH: A cell-surface ligand involved in leukocyte adhesion and inflammation. Its production is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue.,NCI: LFA-1 is a receptor for ICAM1, a surface molecule constitutively expressed on some tissues and induced on others in inflammation. The interaction of LFA-1 with ICAM provides essential accessory adhesion signals in many immune interactions, including those between T- and B-lymphocytes and cytotoxic T-cells and their targets.,NCI: Similar to NCAM, ICAM-1 is a ligand for LFA antigens with a role in leukocyte adhesion and inflammation. Its production in a variety of cells is induced by gamma-interferon and it is required for neutrophil migration into inflamed tissue. ICAM-1 protein is the major human rhinovirus receptor. (from OMIM 147840 and NCI)

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