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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-1-2
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pubmed:abstractText |
The glandular kallikreins are a family of enzymes involved in the post-translational processing of polypeptides. Three family members have been characterized in the human: glandular kallikrein (KLK1) and two genes expressed in the prostate, KLK2 or hGK1 and KLK3 or prostate specific antigen (PSA). Both kallikrein immunoreactivity and KLK1 mRNA have been detected in the rat anterior pituitary and oestrogen induced prolactinomas. Immunoreactive kallikrein has also been reported in prolactin secreting pituitary tumours in humans. In this study we wished to determine whether KLK1 and/or other KLK genes were expressed in human pituitary tumours.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0300-0664
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8849579-Adolescent,
pubmed-meshheading:8849579-Adult,
pubmed-meshheading:8849579-Aged,
pubmed-meshheading:8849579-Aged, 80 and over,
pubmed-meshheading:8849579-Autoradiography,
pubmed-meshheading:8849579-Blotting, Northern,
pubmed-meshheading:8849579-Female,
pubmed-meshheading:8849579-Gene Expression,
pubmed-meshheading:8849579-Humans,
pubmed-meshheading:8849579-Kallikreins,
pubmed-meshheading:8849579-Male,
pubmed-meshheading:8849579-Middle Aged,
pubmed-meshheading:8849579-Pituitary Gland,
pubmed-meshheading:8849579-Pituitary Neoplasms,
pubmed-meshheading:8849579-Polymerase Chain Reaction,
pubmed-meshheading:8849579-Prolactin,
pubmed-meshheading:8849579-Prolactinoma,
pubmed-meshheading:8849579-Prostate-Specific Antigen,
pubmed-meshheading:8849579-Retrospective Studies,
pubmed-meshheading:8849579-Tissue Kallikreins
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pubmed:year |
1996
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pubmed:articleTitle |
Kallikrein gene expression in human pituitary tissues.
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pubmed:affiliation |
Prince Henry's Institute of Medical Research, St. Vincent's Hospital, Victoria, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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