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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-3-4
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pubmed:databankReference |
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pubmed:abstractText |
A search for new genes was performed in a 220-kb region around the tumor necrosis factor gene cluster in the human central major histocompatibility complex region using a cDNA hybridization and selection method. In addition to the seven known genes in this region, we identified a new gene that is preferentially expressed in spleen. We also identified two pseudogenes that have high degrees of homology to cytokeratin and cyclophillin, respectively. Expressed sequences for a human homologue of the mouse B144 gene were also found in the current analysis. RT-PCR analysis showed that B144 is expressed in spleen, in thymus, and prominently in the macrophage cell line, U937. We also independently identified the BAT1 gene to be the well-conserved homologue of a previously described rat liver nuclear protein.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/LST1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/LTB protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Lst1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Ltb protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Lymphotoxin-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Lymphotoxin-beta,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RELB protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Relb protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Relb protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor RelB,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/cyclosporin receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0888-7543
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
215-22
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:8824804-Amino Acid Sequence,
pubmed-meshheading:8824804-Animals,
pubmed-meshheading:8824804-Base Sequence,
pubmed-meshheading:8824804-Blood Proteins,
pubmed-meshheading:8824804-CHO Cells,
pubmed-meshheading:8824804-Cricetinae,
pubmed-meshheading:8824804-DNA, Complementary,
pubmed-meshheading:8824804-Gene Library,
pubmed-meshheading:8824804-Genes, MHC Class I,
pubmed-meshheading:8824804-Genome, Human,
pubmed-meshheading:8824804-Humans,
pubmed-meshheading:8824804-Keratins,
pubmed-meshheading:8824804-Lymphotoxin-alpha,
pubmed-meshheading:8824804-Lymphotoxin-beta,
pubmed-meshheading:8824804-Major Histocompatibility Complex,
pubmed-meshheading:8824804-Membrane Proteins,
pubmed-meshheading:8824804-Mice,
pubmed-meshheading:8824804-Molecular Sequence Data,
pubmed-meshheading:8824804-Multigene Family,
pubmed-meshheading:8824804-Proto-Oncogene Proteins,
pubmed-meshheading:8824804-Rats,
pubmed-meshheading:8824804-Receptors, Immunologic,
pubmed-meshheading:8824804-Transcription Factor RelB,
pubmed-meshheading:8824804-Transcription Factors,
pubmed-meshheading:8824804-Tumor Necrosis Factor-alpha
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pubmed:year |
1996
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pubmed:articleTitle |
Genes in a 220-kb region spanning the TNF cluster in human MHC.
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pubmed:affiliation |
Boyer Center for Molecular Medicine, New Haven, Connecticut 06536-0812, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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