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| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0600465 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0205851 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0003241 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0017278 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0439851 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C1552596 | lld:lifeskim |
| pubmed-article:8813125 | lifeskim:mentions | umls-concept:C1947931 | lld:lifeskim |
| pubmed-article:8813125 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:8813125 | pubmed:dateCreated | 1996-11-21 | lld:pubmed |
| pubmed-article:8813125 | pubmed:abstractText | We report here that 85% of the patients with germ cell tumors (GCTs) produce antibodies directed against Env protein of human endogenous retroviruses. Individuals that received antitumor treatment showed a decrease with time in their antibody titers. Importantly, of the rare cases of non-GCT individuals with Env-antibodies (n= 15, 0.8%), none produced antibodies directed against the transmembrane domain (TM), whereas all tested Env-positive GCT patients (n= 49) generated such antibodies at high titers. TM is required for Env to be expressed at the cell surface. Thus, anti-TM antibodies constitute highly specific markers for GCT and may hint at a function of Env during tumorigenesis. | lld:pubmed |
| pubmed-article:8813125 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8813125 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8813125 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:8813125 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8813125 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:8813125 | pubmed:issn | 0008-5472 | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:HartmannMM | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:SeiteRR | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:SauterMM | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:Mueller-Lantz... | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:BestBB | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:RoemerKK | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:SchommerSS | lld:pubmed |
| pubmed-article:8813125 | pubmed:author | pubmed-author:AftingMM | lld:pubmed |
| pubmed-article:8813125 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8813125 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:8813125 | pubmed:volume | 56 | lld:pubmed |
| pubmed-article:8813125 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8813125 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8813125 | pubmed:pagination | 4362-5 | lld:pubmed |
| pubmed-article:8813125 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:8813125 | pubmed:year | 1996 | lld:pubmed |
| pubmed-article:8813125 | pubmed:articleTitle | Specificity of antibodies directed against Env protein of human endogenous retroviruses in patients with germ cell tumors. | lld:pubmed |
| pubmed-article:8813125 | pubmed:affiliation | Abteilung Virologie, Institut für Medizinische Mikrobiologie und Hygiene, Universitätskliniken des Saarlandes, Homburg/Saar, Germany. | lld:pubmed |
| pubmed-article:8813125 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8813125 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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