|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0007301,
umls-concept:C0025543,
umls-concept:C0029408,
umls-concept:C0030306,
umls-concept:C0035820,
umls-concept:C0039097,
umls-concept:C0205402,
umls-concept:C0441655,
umls-concept:C0681850,
umls-concept:C1550501,
umls-concept:C1555707,
umls-concept:C1705851,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2752151,
umls-concept:C2828366
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1996-12-4
|
|
pubmed:abstractText |
Polymorphonuclear leukocyte (PMN) elastase is able to degrade the extra-cellular matrix components of cartilage. However, in vitro several proteinases can degrade elastin. The purpose of this study was to evaluate the role of the serine proteinases and metalloproteinases in the elastase activity measured in cartilage extracts from patients with osteoarthritis (OA), as well as in synovial fluid (SF) from patients with rheumatoid arthritis (RA) and OA.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0392-856X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
235-41
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:8809436-Adult,
pubmed-meshheading:8809436-Aged,
pubmed-meshheading:8809436-Aged, 80 and over,
pubmed-meshheading:8809436-Arthritis, Rheumatoid,
pubmed-meshheading:8809436-Cartilage,
pubmed-meshheading:8809436-Female,
pubmed-meshheading:8809436-Humans,
pubmed-meshheading:8809436-Male,
pubmed-meshheading:8809436-Metalloendopeptidases,
pubmed-meshheading:8809436-Middle Aged,
pubmed-meshheading:8809436-Osteoarthritis,
pubmed-meshheading:8809436-Pancreatic Elastase,
pubmed-meshheading:8809436-Serine Endopeptidases,
pubmed-meshheading:8809436-Synovial Fluid
|
|
pubmed:articleTitle |
Elastase activity in cartilage extracts and synovial fluids from subjects with osteoarthritis or rheumatoid arthritis: the prominent role of metalloproteinases.
|
|
pubmed:affiliation |
Department of Rheumatology, Hôpital Henri-Mondor, Creteil, France.
|
|
pubmed:publicationType |
Journal Article
|
