Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1996-10-11
|
pubmed:abstractText |
The effect of nursing on plasma luteinizing hormone bioactivity (B-LH) and immunoactivity (I-LH) was assessed at 4 and 6 months post partum in fully nursing women who experienced their first bleeding between months 5 and 6 post partum (n = 6, short amenorrhoea) or after the month 6 (n = 10, long amenorrhoea). Controls were 10 non-nursing fertile women. Blood samples were drawn twice weekly at month 4 post partum and at month 6 post partum. In the nursing women who were cycling at month 6 and in non-nursing women samples were drawn during the follicular phase. I-LH was measured by a time resolved immunofluorometric assay (DELFIA) and B-LH by the mouse Leydig cell assay. Nursing decreased B-LH more than I-LH resulting in a relationship between B-LH and I-LH different to that of non-nursing women (B-LH = 2.84 x I-LH-0.16 and B-LH = 4.27 x I-LH + 3.11 respectively, P < 0.05, by likelihood test). Plasma B-LH or I-LH were similar in nursing women with short or long amenorrhoea. In conclusion, nursing alters the quality of circulating LH, however, the decreased LH steroidogenic potency does not play a role in determining the duration of lactational amenorrhoea.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0268-1161
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2849-53
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8747031-Adult,
pubmed-meshheading:8747031-Amenorrhea,
pubmed-meshheading:8747031-Animals,
pubmed-meshheading:8747031-Biological Assay,
pubmed-meshheading:8747031-Breast Feeding,
pubmed-meshheading:8747031-Female,
pubmed-meshheading:8747031-Fluoroimmunoassay,
pubmed-meshheading:8747031-Humans,
pubmed-meshheading:8747031-Lactation,
pubmed-meshheading:8747031-Leydig Cells,
pubmed-meshheading:8747031-Luteinizing Hormone,
pubmed-meshheading:8747031-Male,
pubmed-meshheading:8747031-Mice,
pubmed-meshheading:8747031-Postpartum Period,
pubmed-meshheading:8747031-Time Factors
|
pubmed:year |
1995
|
pubmed:articleTitle |
Diminished luteinizing hormone biopotency in breastfeeding women.
|
pubmed:affiliation |
Unidad de Reproducción y Desarrollo, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|