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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1996-11-12
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pubmed:abstractText |
We describe here a disease related to mite-associated ulcerative dermatitis in BALB/c mice, a strain previously classified as resistant to this condition. The disease was recognized by pruritic cutaneous pathology and wasting. Pathologic studies showed a marked allergic-type inflammation in the skin. The dominant histologic feature was extensive mast cell infiltration in cutaneous lesions and in lymphoid tissues, associated with a greatly elevated serum IgE concentration. The disease was secondary to infestation with an acarian ectoparasite Myocoptes musculinus, and seemed to represent an allergic reaction to the parasite-derived substances, with an associated wasting syndrome. This condition may be a useful experimental model for allergic diseases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0923-2494
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
147
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8739326-Animals,
pubmed-meshheading:8739326-Dermatitis, Allergic Contact,
pubmed-meshheading:8739326-Female,
pubmed-meshheading:8739326-Immunoglobulin A,
pubmed-meshheading:8739326-Immunoglobulin E,
pubmed-meshheading:8739326-Immunoglobulin G,
pubmed-meshheading:8739326-Lymph Nodes,
pubmed-meshheading:8739326-Male,
pubmed-meshheading:8739326-Mice,
pubmed-meshheading:8739326-Mice, Inbred BALB C,
pubmed-meshheading:8739326-Mite Infestations,
pubmed-meshheading:8739326-Nutrition Disorders,
pubmed-meshheading:8739326-Skin
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pubmed:year |
1996
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pubmed:articleTitle |
Murine acariasis: I. Pathological and clinical evidence suggesting cutaneous allergy and wasting syndrome in BALB/c mouse.
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pubmed:affiliation |
Unité d'Immunobiologie, CNRS URA-1961, Paris.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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