pubmed-article:8647259 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C0025543 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C0172537 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C1618608 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C1417203 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C1624592 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:8647259 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:8647259 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:8647259 | pubmed:dateCreated | 1996-7-23 | lld:pubmed |
pubmed-article:8647259 | pubmed:abstractText | Gelatinase A is secreted as a proenzyme (progelatinase A) which is activated and bound on the surface of tumor and normal cells. We have reported that the expression of a membrane-type-1-matrix metalloproteinase (MT1-MMP) induces activation of progelatinase A. Here we demonstrate that the expression of MT1-MMP in COS-1 cells induces cell-surface binding of progelatinase A which is consequently processed to an intermediate form. Processing from the intermediate to the fully active form is dependent on the gelatinase A concentration. These results suggest that the cell-surface binding concentrates the gelatinase A intermediate form locally to allow autoproteolytic processing to the fully active form. | lld:pubmed |
pubmed-article:8647259 | pubmed:language | eng | lld:pubmed |
pubmed-article:8647259 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:8647259 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:8647259 | pubmed:month | May | lld:pubmed |
pubmed-article:8647259 | pubmed:issn | 0014-5793 | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:ImaiKK | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:SatoHH | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:OkadaYY | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:TakinoTT | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:KinoshitaTT | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:SeikeII | lld:pubmed |
pubmed-article:8647259 | pubmed:author | pubmed-author:Stetler... | lld:pubmed |
pubmed-article:8647259 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:8647259 | pubmed:day | 6 | lld:pubmed |
pubmed-article:8647259 | pubmed:volume | 385 | lld:pubmed |
pubmed-article:8647259 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:8647259 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:8647259 | pubmed:pagination | 238-40 | lld:pubmed |
pubmed-article:8647259 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:8647259 | pubmed:meshHeading | pubmed-meshheading:8647259-... | lld:pubmed |
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pubmed-article:8647259 | pubmed:meshHeading | pubmed-meshheading:8647259-... | lld:pubmed |
pubmed-article:8647259 | pubmed:year | 1996 | lld:pubmed |
pubmed-article:8647259 | pubmed:articleTitle | Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP). | lld:pubmed |
pubmed-article:8647259 | pubmed:affiliation | Department of Molecular Virology and Oncology, Cancer Research Institute, Kanazawa University, Japan. vhsato@icews1.ipc.kanazawa-u.ac.jp | lld:pubmed |
pubmed-article:8647259 | pubmed:publicationType | Journal Article | lld:pubmed |
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