|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002028,
umls-concept:C0007271,
umls-concept:C0008260,
umls-concept:C0017855,
umls-concept:C0032169,
umls-concept:C0038323,
umls-concept:C0205314,
umls-concept:C0220781,
umls-concept:C0244104,
umls-concept:C0332583,
umls-concept:C0598739,
umls-concept:C0679622,
umls-concept:C0682996,
umls-concept:C0996446,
umls-concept:C1704259,
umls-concept:C1705987
|
|
pubmed:dateCreated |
1996-7-18
|
|
pubmed:abstractText |
Isoprenoid biosynthesis was investigated in the green alga Scenedesmus obliquus grown heterotrophically on 13C-labelled glucose and acetate. Several isoprenoid compounds were isolated and investigated by 13C-NMR spectroscopy. According to the 13C-labelling pattern indicated by the 13C-NMR spectra, the biosynthesis of all plastidic isoprenoids investigated (prenyl side-chains of chlorophylls and plastoquinone-9, and the carotenoids beta-carotene and lutein), as well as of the non-plastidic cytoplasmic sterols, does not proceed via the classical acetate/mevalonate pathway (which leads from acetyl-CoA via mevalonate to isopentenyl diphosphate), but via the novel glyceraldehyde 3-phosphate/pyruvate route recently detected in eubacteria. Formation of isopentenyl diphosphate involves the condensation of a C2 unit derived from pyruvate decarboxylation with glyceraldehyde 3-phosphate and a transposition yielding the branched C5 skeleton of isoprenic units.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13607416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13654260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13654322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13654323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13801508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13818862,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-13849151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-14416398,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-3136017,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-4399021,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-4897465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-5660678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-5965341,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-6060454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-7640522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-7791527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8645235-8240251
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0264-6021
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
316 ( Pt 1)
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
73-80
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:8645235-Carbon Isotopes,
pubmed-meshheading:8645235-Carotenoids,
pubmed-meshheading:8645235-Chlorophyll,
pubmed-meshheading:8645235-Chlorophyta,
pubmed-meshheading:8645235-Glyceraldehyde 3-Phosphate,
pubmed-meshheading:8645235-Glyoxylates,
pubmed-meshheading:8645235-Magnetic Resonance Spectroscopy,
pubmed-meshheading:8645235-Pentose Phosphate Pathway,
pubmed-meshheading:8645235-Plastoquinone,
pubmed-meshheading:8645235-Pyruvates,
pubmed-meshheading:8645235-Sterols,
pubmed-meshheading:8645235-Terpenes
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Biosynthesis of isoprenoids (carotenoids, sterols, prenyl side-chains of chlorophylls and plastoquinone) via a novel pyruvate/glyceraldehyde 3-phosphate non-mevalonate pathway in the green alga Scenedesmus obliquus.
|
|
pubmed:affiliation |
Botanisches Institut II, Universität Karlsruhe, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
