|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0014230,
umls-concept:C0033634,
umls-concept:C0079189,
umls-concept:C0086418,
umls-concept:C0086597,
umls-concept:C0162638,
umls-concept:C0441712,
umls-concept:C0596235,
umls-concept:C0683598,
umls-concept:C0851827,
umls-concept:C1378703,
umls-concept:C1456820,
umls-concept:C1518174,
umls-concept:C1701901,
umls-concept:C2346927
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1996-6-26
|
|
pubmed:abstractText |
Because renal cell cancers have been found to be resistant to numerous chemotherapeutic agents, other agents including tumor necrosis factor are now being considered for clinical use. In this study, we used 2 renal cancer cell lines. SK-RC-42 and SK-RC-49, and determined the cytotoxic effects of tumor necrosis factor (TNF) and the possible mechanism of TNF resistance.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0022-5347
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
155
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1779-83
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:8627883-Apoptosis,
pubmed-meshheading:8627883-Endodeoxyribonucleases,
pubmed-meshheading:8627883-Endonucleases,
pubmed-meshheading:8627883-Humans,
pubmed-meshheading:8627883-Kidney Neoplasms,
pubmed-meshheading:8627883-Polymerase Chain Reaction,
pubmed-meshheading:8627883-Protein Kinase C,
pubmed-meshheading:8627883-RNA, Messenger,
pubmed-meshheading:8627883-Tumor Cells, Cultured,
pubmed-meshheading:8627883-Tumor Necrosis Factor-alpha
|
|
pubmed:year |
1996
|
|
pubmed:articleTitle |
Tumor necrosis factor mediates apoptosis via Ca++/Mg++ dependent endonuclease with protein kinase C as a possible mechanism for cytokine resistance in human renal carcinoma cells.
|
|
pubmed:affiliation |
Department of Urology, Mount Sinai School of Medicine, New York, 10029, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
