Linked Life Data

8620839

Source:http://linkedlifedata.com/resource/pubmed/id/8620839

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1996-6-17
pubmed:abstractText
The hedgehog (hh) gene plays a role in regulating cell proliferation and specifying cell identity in diverse systems. We show that hh is expressed at the extreme apical end of Drosophila ovarioles in terminal filament cells and a newly identified group of associated somatic cells. Reducing or ectopically expressing hh affects somatic cells in region 2 of the germarium, 2-5 cells away from the cells in which Hh protein is detected. hh activity stimulates the proliferation of pre-follicle somatic cells, and promotes the specification of polar follicle cells. hh signaling during egg chamber assembly appears to be closely related to, or part of pathways involving the neurogenic genes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0950-1991
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1125-35
pubmed:dateRevised
2009-9-28
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila.
pubmed:affiliation
Molecular Embryology Laboratory, Imperial Cancer Research Fund, Developmental Biology Unit, Department of Zoology, Oxford, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't