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rdf:type |
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lifeskim:mentions |
umls-concept:C0021853,
umls-concept:C0028954,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0040287,
umls-concept:C0220927,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C0458003,
umls-concept:C0596902,
umls-concept:C0678723,
umls-concept:C1519249
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pubmed:issue |
1-2
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pubmed:dateCreated |
1996-5-23
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pubmed:databankReference |
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pubmed:abstractText |
Complementary DNA clones encoding the rat PepT1 small-intestinal oligopeptide transporter were isolated from a jejunal library by cross-hybridization with a rabbit PepT1 cDNA probe. The cDNA sequence indicates that rat PepT1 is composed of 710 amino acids and shows 77% and 83% amino acid sequence identity with rabbit and human PepT1, respectively. Northern blot analysis detected rat PepT1 mRNA in the small intestine and kidney. Intestinal PepT1 mRNA levels were highest in 4-day old rats, and then decreased reaching the adult level by day 28 after birth. These results indicate that the expressions of PepT1 gene change markedly during development.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Oligopeptides,
http://linkedlifedata.com/resource/pubmed/chemical/PepT1 protein,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SLC15A1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Slc15a1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Symporters
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3002
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
1305
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8605246-Age Factors,
pubmed-meshheading:8605246-Animals,
pubmed-meshheading:8605246-Base Sequence,
pubmed-meshheading:8605246-Carrier Proteins,
pubmed-meshheading:8605246-DNA, Complementary,
pubmed-meshheading:8605246-Gene Expression Regulation, Developmental,
pubmed-meshheading:8605246-Humans,
pubmed-meshheading:8605246-Intestine, Small,
pubmed-meshheading:8605246-Jejunum,
pubmed-meshheading:8605246-Kidney,
pubmed-meshheading:8605246-Molecular Sequence Data,
pubmed-meshheading:8605246-Oligopeptides,
pubmed-meshheading:8605246-RNA, Messenger,
pubmed-meshheading:8605246-Rabbits,
pubmed-meshheading:8605246-Rats,
pubmed-meshheading:8605246-Rats, Sprague-Dawley,
pubmed-meshheading:8605246-Sequence Homology, Amino Acid,
pubmed-meshheading:8605246-Symporters,
pubmed-meshheading:8605246-Tissue Distribution
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pubmed:year |
1996
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pubmed:articleTitle |
Sequence, tissue distribution and developmental changes in rat intestinal oligopeptide transporter.
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pubmed:affiliation |
Department of Clinical Nutrition, School of Medicine, Tokushima University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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