rdf:type |
|
lifeskim:mentions |
umls-concept:C0013138,
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0162610,
umls-concept:C0185117,
umls-concept:C0449774,
umls-concept:C0458003,
umls-concept:C0678723,
umls-concept:C1334043,
umls-concept:C2003905,
umls-concept:C2911684
|
pubmed:issue |
3
|
pubmed:dateCreated |
1996-3-20
|
pubmed:databankReference |
|
pubmed:abstractText |
We cloned and sequenced the cDNA which encodes the Caenorhabditis elegans homologue (suf-1) of the Drosophila suppressor of forked (su(f)) gene product. The amino acid sequence deduced from the suf-1 cDNA shares extensive similarity with the su(f) and the human 77K subunit of the CstF, including the proline residues near the carboxy-terminus. Developmental Northern blot analysis showed that a 2.6-kb suf-1 transcript was expressed constitutively from L1 to young adult stages, suggesting it has a housekeeping function in vivo. Furthermore, this idea is consistent with the recent proposition that su(f) homologues play an essential role as a subunit of the cleavage stimulation factor (CstF) during polyadenylation of mRNA precursors.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1340-2838
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
30
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
143-6
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:8581741-Amino Acid Sequence,
pubmed-meshheading:8581741-Animals,
pubmed-meshheading:8581741-Caenorhabditis elegans,
pubmed-meshheading:8581741-DNA, Complementary,
pubmed-meshheading:8581741-Drosophila Proteins,
pubmed-meshheading:8581741-Genes, Helminth,
pubmed-meshheading:8581741-Genes, Suppressor,
pubmed-meshheading:8581741-Helminth Proteins,
pubmed-meshheading:8581741-Molecular Sequence Data,
pubmed-meshheading:8581741-Nuclear Proteins,
pubmed-meshheading:8581741-Proteins,
pubmed-meshheading:8581741-RNA, Messenger,
pubmed-meshheading:8581741-Sequence Analysis, DNA,
pubmed-meshheading:8581741-Sequence Homology, Amino Acid
|
pubmed:year |
1995
|
pubmed:articleTitle |
Developmental expression pattern of the Caenorhabditis elegans homologue of the Drosophila suppressor of forked gene.
|
pubmed:affiliation |
Graduate School of Science and Technology, Kobe University, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|