Linked Life Data

8579585

Source:http://linkedlifedata.com/resource/pubmed/id/8579585

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1996-3-12
pubmed:abstractText
The present study revealed the physiological role of NO as an enhancer of oxygen release from erythrocytes to peripheral tissue by breaking or stretching the heme iron-proximal histidine bond in the alpha subunit of hemoglobin (Hb), while maintaining oxygen binding capacity by restoring the bond in the lungs. Oxygen affinity was significantly decreased in blood containing NO-bound Hb alpha. The results may partly explain nitrosothiols in blood as an NO reservoir for an emergency and why cytokines induce NO synthase in the vascular system during such events as inflammation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0006-291X
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
218
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
749-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Physiological role of nitric oxide as an enhancer of oxygen transfer from erythrocytes to tissues.
pubmed:affiliation
1st Department of Physiology, Medical School, Osaka University, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't