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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1996-3-5
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pubmed:abstractText |
All the conserved regions of HIV gp120 have at least some partial homology with human leukocyte antigen (HLA) class I or class II. One functional similarity is the ability of gp120 and HLA class II to bind CD4. Given the close association between HIV-induced disease and the amount of immune activation and anergy, features closely associated with chronic allogenic stimulation, we asked whether gp120 shared any other properties of HLA, in this case the ability to bind peptides.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0269-9370
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1229-35
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:8561975-Amino Acid Sequence,
pubmed-meshheading:8561975-Binding, Competitive,
pubmed-meshheading:8561975-Epitopes,
pubmed-meshheading:8561975-HIV Envelope Protein gp120,
pubmed-meshheading:8561975-HIV-1,
pubmed-meshheading:8561975-HLA Antigens,
pubmed-meshheading:8561975-Humans,
pubmed-meshheading:8561975-Molecular Sequence Data,
pubmed-meshheading:8561975-Peptides,
pubmed-meshheading:8561975-T-Lymphocytes
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pubmed:year |
1995
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pubmed:articleTitle |
The gp120 envelope of HIV-1 binds peptides in a similar manner to human leukocyte antigens.
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pubmed:affiliation |
Department of Cellular and Molecular Sciences, St George's Hospital Medical School, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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