HIV Envelope Protein gp120

Source:http://linkedlifedata.com/resource/umls/id/C0019691

MSH: External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.,CSP: glycoprotein encoded by HIV envelope gene (env) with a molecular weight of 120,000; interaction between gp120 and CD4 on T-helper cells is involved in the recognition of the cells by HIV and the binding of HIV to those cells.,NCI: A protein produced by the human immunodeficiency virus that functions as a viral anti-receptor attachment protein. The protein is localized to the viral envelope and mediates fusion between viral and cellular membranes.

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