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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1996-2-8
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pubmed:abstractText |
In vitro viability of the endothelium of corneas stored in organ-culture medium is longer than in other storage techniques. This article reports on the clinical results of 20 penetrating keratoplasties performed using corneas stored for > 4 weeks in organ culture. Seventeen of the procedures were elective and three were emergencies. Mean preservation time was 35.6 +/- 7 days (mean +/- SD) and mean follow-up was 16.2 months. During preservation, an endothelial cell loss of 10% was noted. Seventeen grafts remained transparent, and three failed between 3 and 24 months postoperatively. Mean endothelial cell density was 2,153 +/- 372/mm2 at 4 months and 1,854 +/- 390/mm2 at 12 months. Central pachymetry was 548 +/- 53 microns at 4 months and 528 +/- 57 microns at 12 months after surgery. Corneas stored for up to 48 days in organ culture can be used in elective as well as in emergency procedures.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0277-3740
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
463-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8536458-Adolescent,
pubmed-meshheading:8536458-Adult,
pubmed-meshheading:8536458-Aged,
pubmed-meshheading:8536458-Cell Count,
pubmed-meshheading:8536458-Culture Media,
pubmed-meshheading:8536458-Endothelium, Corneal,
pubmed-meshheading:8536458-Female,
pubmed-meshheading:8536458-Graft Survival,
pubmed-meshheading:8536458-Humans,
pubmed-meshheading:8536458-Keratoplasty, Penetrating,
pubmed-meshheading:8536458-Male,
pubmed-meshheading:8536458-Middle Aged,
pubmed-meshheading:8536458-Organ Culture Techniques,
pubmed-meshheading:8536458-Organ Preservation,
pubmed-meshheading:8536458-Time Factors,
pubmed-meshheading:8536458-Tissue Donors
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pubmed:year |
1995
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pubmed:articleTitle |
Corneal grafting of donor tissue preserved for longer than 4 weeks in organ-culture medium.
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pubmed:affiliation |
Department of Ophthalmology, University of Bern, Inselspital, Switzerland.
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pubmed:publicationType |
Journal Article
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