Linked Life Data

8527890

Source:http://linkedlifedata.com/resource/pubmed/id/8527890

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1996-1-26
pubmed:abstractText
Epithelial-mesenchymal transitions play important roles in development and malignancy. Here we discuss molecular events in the control of such transitions: changes in cellular adhesion components, action of oncogenes and tyrosine kinase receptors, as well as activation of transcription factors. In development, epithelial-mesenchymal transitions take place in a temporally and spatially controlled manner, whereas in tumors these changes are highly uncontrolled. Loss of epithelial character is typically observed late in progression of human carcinomas, and correlates there with the acquisition of invasive and metastatic potential.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1023-294X
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-15
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Epithelial-mesenchymal transitions in development and tumor progression.
pubmed:affiliation
Max-Delbrueck-Centrum for Molecular Medicine, Berlin, Germany.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't