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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1993-2-4
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pubmed:databankReference |
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pubmed:abstractText |
We have isolated a yeast SEC23-related clone (Msec23) from mouse fibroblast cDNA library. It has an open reading frame of 1721 bp (64% homologous to SEC23-2.3 kb) which can potentially encode a 64.7 kDa protein (61% homologous to 85.4 kDa product of SEC23). The deduced Msec23 protein (Msec23p) sequence contains three successive Ig-like domains at the N-terminus followed by amphipathic alpha-helical regions, suggesting the potential of Msec23p to interact with other protein components. Further, Msec23 is differentially expressed in mouse tissues with its high level in brain and fibroblasts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-5793
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
315
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pubmed:geneSymbol |
CD4,
Msec23,
SEC23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:8417978-Amino Acid Sequence,
pubmed-meshheading:8417978-Animals,
pubmed-meshheading:8417978-Base Sequence,
pubmed-meshheading:8417978-COP-Coated Vesicles,
pubmed-meshheading:8417978-Cloning, Molecular,
pubmed-meshheading:8417978-DNA,
pubmed-meshheading:8417978-Fungal Proteins,
pubmed-meshheading:8417978-GTPase-Activating Proteins,
pubmed-meshheading:8417978-Gene Expression,
pubmed-meshheading:8417978-Mice,
pubmed-meshheading:8417978-Molecular Sequence Data,
pubmed-meshheading:8417978-Proteins,
pubmed-meshheading:8417978-RNA, Messenger,
pubmed-meshheading:8417978-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:8417978-Sequence Alignment,
pubmed-meshheading:8417978-Sequence Homology, Amino Acid,
pubmed-meshheading:8417978-Tissue Distribution,
pubmed-meshheading:8417978-Vesicular Transport Proteins
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pubmed:year |
1993
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pubmed:articleTitle |
Identification and differential expression of yeast SEC23-related gene (Msec23) in mouse tissues.
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pubmed:affiliation |
Laboratory of Molecular Oncology, Tsukuba Life Science Center, Ibaraki, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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