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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6445
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pubmed:dateCreated |
1993-11-1
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pubmed:abstractText |
The c-Rel protein is able to associate in vitro and in vivo with the TATA-binding protein (TBP) of the TFIID complex. Coexpression of TBP with c-Rel augments transactivation from the kappa B site in Drosophila Schneider cells. DNA-binding mutants of TBP not only fail to cooperate, but they repress transactivation by c-Rel. There may be a direct communication between kappa B enhancer binding proteins and basal transcription factors which leads to enhanced transcription.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0028-0836
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
365
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
412-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8413585-Animals,
pubmed-meshheading:8413585-Base Sequence,
pubmed-meshheading:8413585-Cell Line,
pubmed-meshheading:8413585-DNA-Binding Proteins,
pubmed-meshheading:8413585-Drosophila,
pubmed-meshheading:8413585-Enhancer Elements, Genetic,
pubmed-meshheading:8413585-Escherichia coli,
pubmed-meshheading:8413585-HeLa Cells,
pubmed-meshheading:8413585-Humans,
pubmed-meshheading:8413585-Molecular Sequence Data,
pubmed-meshheading:8413585-Mutation,
pubmed-meshheading:8413585-NF-kappa B,
pubmed-meshheading:8413585-Oligodeoxyribonucleotides,
pubmed-meshheading:8413585-Precipitin Tests,
pubmed-meshheading:8413585-Protein Binding,
pubmed-meshheading:8413585-Proto-Oncogene Proteins,
pubmed-meshheading:8413585-Proto-Oncogene Proteins c-rel,
pubmed-meshheading:8413585-Recombinant Proteins,
pubmed-meshheading:8413585-Saccharomyces cerevisiae,
pubmed-meshheading:8413585-TATA-Box Binding Protein,
pubmed-meshheading:8413585-Transcription, Genetic,
pubmed-meshheading:8413585-Transcription Factor TFIID,
pubmed-meshheading:8413585-Transcription Factors,
pubmed-meshheading:8413585-Transcriptional Activation,
pubmed-meshheading:8413585-Transfection
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pubmed:year |
1993
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pubmed:articleTitle |
Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B.
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pubmed:affiliation |
Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92138.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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