TATA-Box Binding Protein

Source:http://linkedlifedata.com/resource/umls/id/C0144555

NCI: TATA-box-binding protein (339 aa, ~38 kDa) is encoded by the human TBP gene. This protein is involved in both DNA binding and gene transcription initiation.,MSH: A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.

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