Linked Life Data

8319924

Source:http://linkedlifedata.com/resource/pubmed/id/8319924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1993-8-4
pubmed:abstractText
The activities of reactive oxygen species scavenging enzymes, superoxide dismutases (SODs) and catalase (in cells of two melanomas (mouse B16 and human SK23) and in Chinese hamster ovary (CHO) cells were examined. Melanoma cells are relatively depleted in activities of superoxide dismutases and catalase as compared to CHO cells. Short equitoxic (500 microM for CHO and B16 cells and 5 microM for SK23 cells) paraquat treatment (15 min before the X-irradiation, 45 min in postirradiation period--the total time of treatment was 1 h) caused an increase in radiation resistance, measured as colony forming ability, in two of the three lines examined. It is proposed that PQ may exert its radioprotective effect by induction of antioxidant enzymes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
8755-0199
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
139-45
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
The effect of paraquat on the radiosensitivity of melanoma cells: the role of superoxide dismutase & catalase.
pubmed:affiliation
Department of Radiation Biology and Health Protection, Institute of Nuclear Chemistry and Technology, Warsaw, Poland.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't