| pubmed-article:8282790 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0034896 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0025148 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0001629 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0205101 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C1550278 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0037473 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0041942 | lld:lifeskim |
| pubmed-article:8282790 | lifeskim:mentions | umls-concept:C0205386 | lld:lifeskim |
| pubmed-article:8282790 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:8282790 | pubmed:dateCreated | 1994-2-17 | lld:pubmed |
| pubmed-article:8282790 | pubmed:abstractText | We dissected and perfused outer medullary vasa recta (OMVR) from vascular bundles in the rat. Permeabilities of sodium (PNa) and urea (Pu) were simultaneously determined from the lumen-to-bath efflux of 22Na and [14C]urea. PNa and Pu were also measured by in vivo microperfusion of descending (DVR) and ascending vasa recta (AVR) at the papillary tip of Munich-Wistar rats. In some OMVR PNa was indistinguishable from zero. The mean +/- SE of PNa (x 10(-5), cm/s) in OMVR was 76 +/- 9. Pu in OMVR was always very high (x 10(-5), cm/s), 360 +/- 14. There was no correlation between OMVR PNa and Pu. Inner medullary AVR and DVR had PNa of 115 +/- 10 and 75 +/- 10, respectively, and Pu of 121 +/- 10 and 76 +/- 11, respectively. PNa and Pu in papillary vasa recta were always nearly identical and highly correlated. Transport of [14C] urea in OMVR was reversibly inhibited by addition of unlabeled urea or phloretin to the bath and lumen, providing evidence for carrier-mediated transport. These data suggest that sodium and urea might traverse the wall of inner medullary vasa recta by a paracellular pathway while urea also crosses by a transcellular route in OMVR. Electron microscopic examination of seven in vitro perfused OMVR revealed no fenestrations and exposure of these vessels to 10 microM calcium ionophore A23187 or 1 nM angiotensin II resulted in reversible contraction, suggesting that in vitro perfused OMVR are DVR only. | lld:pubmed |
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| pubmed-article:8282790 | pubmed:language | eng | lld:pubmed |
| pubmed-article:8282790 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:8282790 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:8282790 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:8282790 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:8282790 | pubmed:issn | 0021-9738 | lld:pubmed |
| pubmed-article:8282790 | pubmed:author | pubmed-author:JamisonR LRL | lld:pubmed |
| pubmed-article:8282790 | pubmed:author | pubmed-author:MyersR LRL | lld:pubmed |
| pubmed-article:8282790 | pubmed:author | pubmed-author:PalloneT LTL | lld:pubmed |
| pubmed-article:8282790 | pubmed:author | pubmed-author:WorkJJ | lld:pubmed |
| pubmed-article:8282790 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:8282790 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:8282790 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:8282790 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:8282790 | pubmed:pagination | 212-22 | lld:pubmed |
| pubmed-article:8282790 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:8282790 | pubmed:year | 1994 | lld:pubmed |
| pubmed-article:8282790 | pubmed:articleTitle | Transport of sodium and urea in outer medullary descending vasa recta. | lld:pubmed |
| pubmed-article:8282790 | pubmed:affiliation | Division of Nephrology, M.S. Hershey Medical Center, Pennsylvania State University, Hershey 17033. | lld:pubmed |
| pubmed-article:8282790 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:8282790 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:8282790 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:8282790 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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