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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1994-2-10
|
| pubmed:abstractText |
A review of 315 fine-needle aspiration cytologies (FNAC) carried out from 1984 through 1992 in 157 patients with suspected metastatic melanoma was carried out: 176 results were confirmed by histological examination and 139 by clinical follow-up. In the first period, from 1984 through 1988, we observed 5 false-negative results out of 123 evaluable FNACs. All were caused by technical failure. In the second period, from 1988 through 1992, all fine-needle biopsies of impalpable masses were done with ultrasound guidance. Thus, we were able to avoid further false-negative results. No errors in interpretation were found. We obtained 219 true-positive and 91 true-negative results with 97.8% sensitivity, 100% specificity, 98.4% accuracy, 100% positive and 94.8% negative predictive value. In 3 cases with metastatic melanoma the cytological diagnosis only was 'malignant tumor', while in another 5 patients the cytodiagnosis of melanoma was not definitive. Immunocytology was helpful in these cases in identifying melanoma. FNAC allowed the correct diagnosis of a second malignancy in 4 cases (one papillary thyroid cancer, one Hodgkin's disease, two non-Hodgkin's lymphomas). No complications occurred. In our opinion, FNAC--for poorly defined lesions with ultrasound guidance--is a very rapid, safe and accurate method that allows reliable diagnosis of metastatic melanoma.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0017-8470
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
44
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
703-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8276588-Adolescent,
pubmed-meshheading:8276588-Adult,
pubmed-meshheading:8276588-Aged,
pubmed-meshheading:8276588-Aged, 80 and over,
pubmed-meshheading:8276588-Biopsy, Needle,
pubmed-meshheading:8276588-Diagnosis, Differential,
pubmed-meshheading:8276588-Female,
pubmed-meshheading:8276588-Humans,
pubmed-meshheading:8276588-Lymph Nodes,
pubmed-meshheading:8276588-Lymphatic Metastasis,
pubmed-meshheading:8276588-Male,
pubmed-meshheading:8276588-Melanoma,
pubmed-meshheading:8276588-Middle Aged,
pubmed-meshheading:8276588-Neoplasm Recurrence, Local,
pubmed-meshheading:8276588-Neoplasm Staging,
pubmed-meshheading:8276588-Skin,
pubmed-meshheading:8276588-Skin Neoplasms,
pubmed-meshheading:8276588-Soft Tissue Neoplasms,
pubmed-meshheading:8276588-Transducers,
pubmed-meshheading:8276588-Ultrasonography
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
[Fine needle aspiration cytology of metastatic malignant melanoma. Improvement of results with ultrasound control].
|
| pubmed:affiliation |
Medizinische Klinik, Bundeswehrkrankenhauses Ulm.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|