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pubmed-article:8223252pubmed:abstractTextThe segment polarity gene wingless (wg) is expressed in a complex pattern during embryogenesis suggesting that it plays multiple roles in the development of the embryo. The best characterized of these is its role in cell pattening in each parasegment, a process that requires the activity of other segment polarity genes including patched (ptc) and hedgehog (hh). Here we present further evidence that ptc and hh encode components of a signal transduction pathway that regulate the expression of wg transcription following its activation by pair-rule genes. We also show that most other aspects of wg expression are independent of this regulatory network.lld:pubmed
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pubmed-article:8223252pubmed:articleTitleRegulation of wingless transcription in the Drosophila embryo.lld:pubmed
pubmed-article:8223252pubmed:affiliationICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.lld:pubmed
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