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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1993-11-29
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pubmed:abstractText |
The segment polarity gene wingless (wg) is expressed in a complex pattern during embryogenesis suggesting that it plays multiple roles in the development of the embryo. The best characterized of these is its role in cell pattening in each parasegment, a process that requires the activity of other segment polarity genes including patched (ptc) and hedgehog (hh). Here we present further evidence that ptc and hh encode components of a signal transduction pathway that regulate the expression of wg transcription following its activation by pair-rule genes. We also show that most other aspects of wg expression are independent of this regulatory network.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0950-1991
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:geneSymbol |
ptc,
wg
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-91
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:8223252-Animals,
pubmed-meshheading:8223252-Drosophila,
pubmed-meshheading:8223252-Drosophila Proteins,
pubmed-meshheading:8223252-Gene Expression Regulation,
pubmed-meshheading:8223252-Genes, Insect,
pubmed-meshheading:8223252-In Situ Hybridization,
pubmed-meshheading:8223252-Proto-Oncogene Proteins,
pubmed-meshheading:8223252-Signal Transduction,
pubmed-meshheading:8223252-Transcription, Genetic,
pubmed-meshheading:8223252-Wnt1 Protein
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pubmed:year |
1993
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pubmed:articleTitle |
Regulation of wingless transcription in the Drosophila embryo.
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pubmed:affiliation |
ICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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